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Diarrhoea and vomiting caused by gastroenteritis in children under 5 years




            Reliability               Reliability refers to a method of measurement that consistently gives the same
                                      results. For example, someone who has a high score on one occasion tends to
                                      have a high score if measured on another occasion very soon afterwards. With
                                      physical assessments it is possible for different clinicians to make independent
                                      assessments in quick succession, and if their assessments tend to agree then the
                                      method of assessment is said to be reliable.
            Retrospective study       A retrospective study deals with events or outcomes that have already occurred
                                      in  the  past  and  does  not  involve  studying  future  events. This  contrasts  with
                                      studies that are prospective.
            Risk                      See absoute risk or risk.
            Risk difference (RD)      The absolute difference between the risks of two groups. Also known as absolute
                                      risk difference.
            Royal Colleges            In the UK medical/nursing world the term ‘royal colleges’, as for example in ‘The
                                      Royal College of …’, refers to organisations that usually combine an educational
                                      standards and examination role with the promotion of professional standards.
            Safety netting            The provision of support for patients in whom the clinician has some uncertainty
                                      as to whether the patient has a self-limiting illness and is concerned that their
                                      condition  may  deteriorate.  Safety  netting  may  take  a  number  of  forms,  such
                                      as dialogue with the patient or carer about symptoms and signs to watch for,
                                      advice about when to seek further medical attention, review after a set period,
                                      and liaising with other healthcare services.
            Sample                    A  part  of  the  study’s  target  population  from  which  the  subjects  of  the  study
                                      will be recruited. If subjects are drawn in an unbiased way from a particular
                                      population, the results can be generalised from the sample to the population as
                                      a whole.
            Scottish Intercollegiate   SIGN was established in 1993 to sponsor and support the development of evidence-
            Guidelines Network (SIGN)  based clinical guidelines for the NHS in Scotland.
            Secondary care            Care provided in hospitals.
            Secondary outcome         An outcome deemed a priori as less important than the primary outcome and is
                                      measured to evaluate additional effects of the intervention.
            Selection bias            A type of bias that occurs if:
                                     •  the characteristics of the sample differ from those of the wider population from
                                        which the sample has been drawn, or
                                     •  there  are  systematic  differences  between  comparison  groups  in  a  study  in
                                        terms of prognosis or responsiveness to treatment.
            Selection criteria        Explicit standards used by guideline development groups to decide which studies
                                      should be included and excluded from consideration as potential sources of
                                      evidence.
            Semi-structured interview   Structured interviews involve asking people pre-set questions. A semi-structured
                                      interview allows more flexibility than a structured interview. The interviewer asks
                                      a number of open-ended questions, following up areas of interest in response to
                                      the information given by the respondent.
            Sensitivity               In  diagnostic  testing,  this  refers  to  the  proportion  of  cases  with  the  target
                                      condition correctly identified by the diagnostic test out of all the cases that have
                                      the target condition.
            Shock                     A pathological condition in which there is inadequate blood perfusion of the
                                      vital organs.
            Single-blind study        A study in which either the subject (patient/participant) or the observer (clinician/
                                      investigator)  is  not  aware  of  which  treatment  or  intervention  the  subject  is
                                      receiving.
            Skin turgor               A term used to describe a physical characteristic of the skin. In patients with
                                      clinical dehydration, skin turgor may be reduced, so that when a fold of skin is
                                      gently pinched and then released it fails to immediately retract in the normal
                                      way, but rather retains a ridged appearance for a variable period owing to a
                                      reduction in its fluid content.




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