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Diarrhoea and vomiting caused by gastroenteritis in children under 5 years




                        and  solid  feeds. The  GDG  considered  that  cessation  of  breastfeeding  even  for  a  few  hours
                        could pose significant difficulties for mother and child (for example, discomfort and possible
                        risk to maintaining breastfeeding). For these reasons, breastfeeding should continue if possible
                        throughout the period of rehydration.
                        With regard to milk formula feeds and solid foods, different considerations apply. Such feeds
                        could result in a reduced rate of gastric emptying. Delayed emptying might increase the risk of
                        vomiting and consequently of ORT failure. The GDG considered that the nutritional significance
                        of any milk or solid food taken in the 3–4 hour rehydration phase of therapy is likely to be small.
                        The GDG therefore agreed that feeds other than breast milk should be discontinued during the
                        rehydration phase of fluid therapy. An exception to this could be made in children without red
                        flag symptoms or signs of dehydration (see Table 4.6). If such children do not take an adequate
                        amount  of  ORS  solution  they  could  be  given  supplementary  feeds  with  their  usual  fluids  –
                        generally milk or water. However, they should not be given any fruit juices or carbonated drinks
                        as these are often of high osmolarity and can worsen diarrhoea.

                         Recommendation on feeding during rehydration
                         During rehydration therapy:

                         •  continue breastfeeding
                         •  do not give solid foods
                         •  in children with red flag symptoms or signs (see Table 4.6), do not give oral fluids other
                           than ORS solution
                         •  in children without red flag symptoms or signs (see Table 4.6), do not routinely give oral
                           fluids other than ORS solution; however, consider supplementation with the child’s usual
                           fluids (including milk feeds or water, but not fruit juices or carbonated drinks) if they
                           consistently refuse ORS solution.

            6.2         Feeding following rehydration


                        The  timing  of  the  re-introduction  of  nutrition,  whether  as  milk  feeds  or  solid  foods,  may  be
                        important. Prolonged withholding of food may result in malnutrition. It is also clear that the
                        presence of nutrients in the gut promotes mucosal health and absorptive function. It is important
                        to appreciate that diarrhoea often persists for days but this does not usually indicate clinically
                        significant  malabsorption.  A  more  important  indicator  of  recovery  is  the  achievement  of
                        appropriate weight gain.
                        The common practice of diluting feeds during the process of re-introduction could have adverse
                        consequences for recovery. It has also been suggested that the use of specialised soy protein
                        or  protein  hydrolysate  formulas  may  reduce  the  risk  of  complications  during  recovery  from
                        gastroenteritis. Lactose-free or lactose-reduced formulas have been recommended to reduce the
                        risk of diarrhoea from lactose malabsorption.

                        Solid foods may be important during the recovery phase, not only in the prevention of malnutrition
                        but also in promoting mucosal recovery. There have been suggestions that specific foodstuffs
                        could also promote recovery. In some cultures, the use of specific foods such as rice and cereal-
                        based foods has been promoted. The evidence available regarding such practices was identified
                        in order to inform recommendations.

                         Clinical questions
                         •  Does early versus late re-introduction of feed affect outcomes?
                         •  What milk or other liquid feeds should be allowed?
                         •  Should solid foods be allowed? If yes, what foods should be allowed?
                         •  What are the indications for use of a specialised formula?

                        Out of 71 retrieved papers, 28 were found to be suitable for inclusion and addressed maintenance
                        feeding following the rehydration phase of therapy. Five RCTs compared the effect of early versus
                        late  reintroduction  of  feed  on  clinical  outcome  while  six  RCTs  described  graded  re-feeding
                        versus full-strength re-feeding regimens. One RCT described the addition of fruit juices to the



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