Page 48 - Depression in adults: treatment and management

Depression in adults: treatment and management (NG222)

Other things to think Other things to think
TTreatment reatment How is this delivHow is this delivered? ered? KKeey features y features
about about

• Choice of

treatment will
depend on
preference for

• Usually taken for at least specific medication
6 months (and for some effects such as
time after symptoms • SSRIs are generally sedation,
remit). well tolerated, have concomitant

• Can be a selective a good safety profile illnesses or
medications,
serotonin reuptake and should be suicide risk and
inhibitor (SSRI), considered as the previous history of

serotonin–norepinephrine first choice for most response to
Antidepressant reuptake inhibitor (SNRI), people. antidepressant
medication or other antidepressant if • Tricyclic medicines.

indicated based on antidepressant
previous clinical and (TCAs) are • Minimal time
treatment history. dangerous in commitment,

• See the recommendations overdose, although although regular
reviews needed
on starting and stopping lofepramine has the (especially when
antidepressant best safety profile. starting and
medication for more stopping

details. treatment).

• Benefits should be

felt within
4 weeks.

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