Page 190 - Pagetit
P. 190

6. CONCURRENT DISORDERS



                                                CHAPTER 6


                                    Concurrent Disorders









                     Introduction
                     Over the past decade, there has been increasing awareness that there is a
                     high degree of comorbidity (co-occurrence in the same individual) between
                     various psychiatric disorders. That is, individuals with a history of one
                     psychiatric disorder are much more likely than would be expected by chance
                     to have a history of another psychiatric disorder (Robins & Regier, 1991;
                     Kessler et al., 1994). Most relevant to this report are data indicating that there
                     is high comorbidity between any mental disorder and substance dependence.
                     Specifically, these data indicate that:
                        • Lifetime prevalence of alcohol disorder is 22.3% for individuals with
                           any mental disorder compared to 14% for the general population, and
                           that the odds of having an alcohol disorder if a person also has any
                           mental disorder are 2.3 times higher than if there is no mental disorder
                           (Regier et al., 1990).
                        • Among people with substance (except alcohol) use disorders, 53% also
                           suffer from at least one other mental disorder, with an odds ratio of 4.5
                           when compared to people without substance (other than alcohol)
                           disorders (Regier et al., 1990).

                        • Higher percentages of people with mental illness, particularly those
                           with schizophrenia, smoke tobacco than in the general population and
                           among people without mental illness. Depending on the particular
                           mental illness, it has been reported that 26–88% of psychiatric patients
                           smoke compared to 20–30% of the general population (Glassman et
                           al., 1990; Breslau, 1995; Hughes et al., 1986).
                        Despite the fact that the majority of studies were undertaken in a few
                     developed countries and the degree of comorbidity in many cultures is vastly
                     unknown, this high degree of comorbidity between mental disorders and
                     substance use disorders strongly suggests that these disorders are linked
                     because of shared neurobiological and behavioural abnormalities. Although
                     most scientists and clinicians would agree with this suggestion, it remains
                     unclear as to what the causal factors are. That is, does mental illness lead to
                     substance dependence, or does substance dependence lead to mental illness,
                     or are both mental illness and substance dependence independent


                                                     169




          Chapter_6                169                             19.1.2004, 11:48
   185   186   187   188   189   190   191   192   193   194   195