Page 130 - 85 cell signalling pathways

Cell Signalling Biology Michael J. Berridge Module 2 Cell Signalling Pathways 2 130

Metabolic messengers Rutter, G.A., da Silva Xavier, G. and Leclerc, I. (2003) Roles of
Zima, A.V., Kocksk¨ amper, J., Meijia-Alvarez, R. and Blatter, L.A. (2003) 5’-AMP-activated protein kinase (AMPK) in mammalian glucose
Pyruvate modulates cardiac sarcoplasmic reticulum Ca 2 + release in homoeostasis. Biochem. J. 375:1–16.
rats via mitochondria-dependent and -independent mechanisms.
J. Physiol. 550:765–783.

Adenosine monophosphate (AMP)
Hardie, D.G. (2005) New roles for the LKB1→AMPK pathway. Curr. Sterol sensing and the regulation of cholesterol
Opin. Cell Biol. 17:167–173. biosynthesis
Kahn, B.B., Alquier, T., Carling, D. and Hardie, D.G. (2005) Brown, M.S. and Goldstein, J.L. (1999) A proteolytic pathway that
AMP-activated protein kinase: ancient energy gauge provides clues to controls the cholesterol content of membranes, cells, and blood.
modern understanding of metabolism. Cell Metab. 1:15–25. Proc. Natl. Acad. Sci. U.S.A 96:11041–11048.

C 2012 Portland Press Limited www.cellsignallingbiology.org