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Index

pyrimethamine (sulfadoxine-) 1, 3, 7, 14–17, 19, 21, 25, 27, 29, 33, 34, 37, 41, 48, 49, 52, 56, 58, 65,
76–78, 80, 101, 110, 111, 125, 134, 168, 172

Q
quinidine 31, 37, 38, 41, 43, 86, 90, 92
quinine 3, 7, 18, 19, 26–28, 31, 32, 34, 37–43, 47, 49, 57, 65, 70, 79, 86, 90–92, 100–102, 111, 127, 154–162, 169
plus tetracycline 18, 19

R

rapid diagnostic tests (RDT) 10–13, 48, 24, 54, 55, 118, 119, 167
recrudescence 6–8, 17, 18, 36, 48, 53, 125, 169
rectal (intra-) route 22–24, 29, 30, 32, 34, 37, 39–43, 85, 99
diazepam/benzodiazepines 23, 43, 46
artemisinin/artesunate 24, 29, 30, 32, 37, 39, 40, 42, 57, 81, 83, 84, 161
renal failure 5, 39, 43, 44, 53, 91, 93, 95
resistance 1, 2, 6, 7, 8, 13–15, 17, 19–23, 25, 27, 30, 37, 48, 49, 53, 54, 56, 59, 71–73, 75, 77, 80, 89, 113, 114, 115,
120, 122–131, 135, 137, 143, 151, 167, 168, 169, 171, 172, 173
amodiaquine 17, 20
artemisinin 17, 19, 21
chloroquine 17, 20, 48, 53, 56, 113, 122, 125, 129
emergence 13, 30, 49, 124, 125, 128–130
mefloquine 113, 129
proguanil 48, 89
sulfadoxine-pyrimethamine 14, 17, 21, 48, 49
respiratory 35, 45, 46, 53, 78, 80, 96
Reye’s syndrome 23

S
Salmonella 44, 46
second-line treatment 18, 19
semi-immune 22
septicaemia 37, 44, 99
severe falciparum/vivax malaria see malaria
standard dose 29, 158
stillbirth 27
strong recommendation 14, 15, 16, 38, 135, 145, 155, 178
sulfadoxine 3, 7, 14, 15, 16, 17, 19, 21, 25, 33, 34, 37, 48, 49, 52, 56, 65, 76, 77, 78, 101, 110, 125, 134, 168, 172
-pyrimethamine 1, 3, 7, 14–17, 19, 21, 25, 33, 34, 37, 48, 49, 52, 56, 58, 65, 101, 110, 125, 134, 168,
172, 193
suppositories 23, 40, 57, 162, 193
T

tafenoquine 49, 170
teratogenicity 26
tetracycline(s) 14, 18, 19, 21, 27–29, 32, 34, 39, 88, 92–95, 101, 102, 193
193