Page 165 - HIV/AIDS Guidelines

Caring for Patients with HIV and Tuberculosis
Close collaboration among clinicians, health care institutions, and public health programs involved in the
diagnosis and treatment of HIV-infected patients with active TB disease is necessary in order to integrate
care and improve medication adherence and TB treatment completion rates, reduce drug toxicities, and
maximize HIV outcomes. HIV-infected patients with active TB disease should receive treatment support,
including adherence counseling and DOT, corresponding to their needs (AII). ART simplification or use of
coformulated fixed-dose combinations also may help to improve drug adherence.

References

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2. Perlman DC, el-Sadr WM, Nelson ET, et al. Variation of chest radiographic patterns in pulmonary tuberculosis by degree
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Research on AIDS (CPCRA). The AIDS Clinical Trials Group (ACTG). Clin Infect Dis. Aug 1997;25(2):242-246.

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virus infection after tuberculosis. Am J Respir Crit Care Med. Jan 1995;151(1):129-135.

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4):1-207; quiz CE201-204.
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tuberculosis. N Engl J Med. Oct 20 2011;365(16):1471-1481.

8. Havlir DV, Kendall MA, Ive P, et al. Timing of antiretroviral therapy for HIV-1 infection and tuberculosis. N Engl J Med.
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9. Gandhi NR, Shah NS, Andrews JR, et al. HIV coinfection in multidrug- and extensively drug-resistant tuberculosis
results in high early mortality. Am J Respir Crit Care Med. Jan 1 2010;181(1):80-86.

10. Dheda K, Shean K, Zumla A, et al. Early treatment outcomes and HIV status of patients with extensively drug-resistant
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11. Panel on Treatment of HIV-Infected Pregnant Women and Prevention of Perinatal Transmission. Recommendations for
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