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             Drug Effectiveness Review Project




























































                          Alzheimer Drugs   Authors: Watkins et al. 80    Year: 1994   Country: US  Alzheimer’s Association Inc., Chicago, IL; National Institute on Aging, Washington, DC; Parke- Davis/Warner-Lambert Co, Ann Arbor, MI; Advanced Nutritional Technologies, Elizabeth, NJ  Study design: Retrospective data-analysis of RCTs  Number of patients: 2,446  To analyze the hepatic effects of TAC treatment in patients with AD     Three published trials:  Davis et al. 1992; Farlow et al. 1992; Knapp et al 1994     Data from two unpublished trials by coauthor Knapp also included      1992-1994  Placebo-controlled trials of TA

























             Final Report Update 1     Adverse Events      STUDY:      FUNDING:      DESIGN:          AIMS OF REVIEW:   STUDIES INCLUDED IN   META-ANALYSIS      TIME PERIOD COVERED:     CHARACTERISTICS OF  INCLUDED STUDIES:     CHARACTERISTICS OF  INCLUDED POPULATIONS:           Alzheimer's Drugs
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