Page 267 - Drug Class Review
P. 267

Drug Effectiveness Review Project










                                 donepezil      16.1   15.5   7.4   5.6   5.0   5.0   5.0   5.0   Post randomization exclusions: N/A   Overall loss to follow-up: N/A  Loss to follow-up differential high: N/A         donepezil      N/A      N/A      Page 164 of 205






                                                                            ITT: N/A


                                                                  N/A             N/A      N/A      N/A                         N/A

















             Final Report Update 1     Authors: Dunn et al.   Year:2000   ADVERSE EVENTS:   Overall adverse effects reported:   Nausea/Vomiting   •   Diarrhea   •   Malaise/lassitude   •  Respiratory tract infection   •   Dizziness   •   Insomnia   •   Micturition disorder   •  Significant differences in adverse   events:      ANALYSIS:    ADEQUATE RANDOMIZATION:   ADEQUATE ALLOCATION   CONCEALMENT:  BLINDING OF OUTCOME   ASSESSORS:   ATTRITION (overall):     ATTRITION (treatment specific):   Loss to follow-up:   Withdrawals due to adverse events:        QUALITY RATING:      *primary outcome measures         Alzheimer's Drug
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