Page 716 - 16Neonatal Jaundice_compressed
P. 716
Neonatal jaundice
Transepidermal Passes across the epidermal layer (skin) to the surrounding
atmosphere via diffusion and evaporation processes.
Triple blind study A study in which the statistical analysis is carried out without
knowing which treatment patients received, in addition to the
patients and investigators/clinicians being unaware which treatment
patients were getting.
Unconjugated bilirubin This is the term used to describe bilirubin which has not been
processed by the liver. Normally unconjugated bilirubin is taken up
by the liver where an enzyme produces conjugated bilirubin. It is
then transported by the biliary system to the intestine and excreted.
Unconjugated hyperbilirubinaemia arises if the liver cannot handle
the amount of unconjugated bilirubin presented to it. This can occur
as a result of excessive red blood cell breakdown – (haemolysis)
and/or because of immaturity of the liver enzymes involved in
conjugation.
Univariate analysis Analysis of data on a single variable at a time
Urinary tract infection A bacterial infection that affects any part of the urinary tract.
Validity Assessment of how well a tool or instrument measures what it is
intended to measure. See also External validity, Internal validity.
Variable A measurement that can vary within a study, e.g. the age of
participants. Variability is present when differences can be seen
between different people or within the same person over time, with
respect to any characteristic or feature which can be assessed or
measured.
Vasodilator effects Refers to widening of blood vessels
510
