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Appendix J




 Excluded studies








 Which factors affect the relationship between neonatal hyperbilirubinaemia and kernicterus or other adverse outcomes (neurodevelopmental, auditory)?

 Reference                        Reason for exclusion
 Bertini G, Dani C, Tronchin M et al. Is breastfeeding really favoring early neonatal jaundice? Pediatrics 2001; 107:(3)E41.   No analysis for confounding variables
 Beutner D, Foerst A, Lang-Roth R et al. Risk factors for auditory neuropathy/auditory synaptopathy. ORL 2007; 69:(4)239–44.   No adjustment for confounding variables
 Bhutani VK and Johnson LH. Jaundice technologies: prediction of hyperbilirubinemia in term and near-term newborns. Journal of  Overview
 Perinatology 2001; 21 Suppl 1:S76-S82.
 Bhutani VK. Combining clinical risk factors with serum bilirubin levels to predict hyperbilirubinemia in newborns. Journal of   Synopsis
 Pediatrics 2005; 147:(1)123–4.
 Blackmon LR, Fanaroff AA, and Raju TNK. Research on prevention of bilirubin-induced brain injury and kernicterus: National   Overview of jaundice research
 Institute of Child Health and Human Development conference executive summary.  Pediatrics 2004; 114:(1)229–33.
 Brites D, Fernandes A, Falcao AS et al. Biological risks for neurological abnormalities associated with hyperbilirubinemia. J   Overview - Background
 Perinatol 0 AD; 29:(S1)S8-S13.
 Cronin CM, Brown DR, and hdab-Barmada M. Risk factors associated with kernicterus in the newborn infant: importance of   Benzyl alcohol as a risk factor for kernicterus
 benzyl alcohol exposure. American Journal of Perinatology 1991; 8:(2)80–5.
 De Vries LS, Lary S, Whitelaw AG et al. Relationship of serum bilirubin levels and hearing impairment in newborn infants. Early   Outcome not of interest to this guideline
 Human Development 1987; 15:(5)269–77.
 Ding G, Zhang S, Yao D et al.  An epidemiological survey on neonatal jaundice in China. Chinese Medical Journal 2001;   No adjustment for confounding variables
 114:(4)344–7.
 Frishberg Y, Zelicovic I, Merlob P et al. Hyperbilirubnemia and influencing factors in term infants. Israel Journal of Medical   Confounders not controlled for
 Sciences 1989; 25:(1)28–31.
 Gagnon AJ, Waghorn K, Jones MA et al. Indicators nurses employ in deciding to test for hyperbilirubinemia. JOGNN - Journal of  Background
 Obstetric, Gynecologic, and Neonatal Nursing 2001; 30:(6)626–33.
 Gartner LM and Arias IM. Studies of prolonged neonatal jaundice in the breast-fed infant. Journal of Pediatrics 1966; 68:(1)54–66.  No adjustment for confounders
 Geiger AM, Petitti DB, and Yao JF. Rehospitalisation for neonatal jaundice: risk factors and outcomes. Paediatric and Perinatal   Risk factors for jaundice readmission –
 Epidemiology 2001; 15:(4)352–8.   confounders not controlled for



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