Page 270 - 16Neonatal Jaundice_compressed

Neonatal jaundice

Bibliographic details Study type & Patient characteristics Test, Reference Standard, Results Reviewers Comments
Evidence level Threshold for a positive test
RISK FACTOR SCORE

c-statistic 0.71 (0.66–0.76)

Risk index score 0–7
+LR: 0.1

Risk index score 8–11
+LR: 0.4

Risk index score 12–15
+LR: 0.9

Risk index score 16–19
+LR: 2.0

Risk index score 20–23
+LR: 2.6

Risk index score > 24
+LR: 3.2

PRE-DISCHARGE TSB

c-statistic 0.83 (0.80–0.86)

th
TSB centile 0–40
+LR: 0.05

th
TSB centile 41–75
+LR: 0.2

th
TSB centile 76–95
+LR: 2.2

th
TSB centile > 95
+LR: 9.4

Keren R et al.; Study Type: Infants managed exclusively in the 1) Factors associated with Prevalence of significant Unselected population
Prospective cohort well infants nursery of an urban significant hyperbilirubinaemia in hyperbilirubinaemia (stratified sampling) with well
Year: 2008 study tertiary care hospital with univariate analysis entered into defined exclusion criteria
GA = 36 weeks and BW = 2000 g or regression modeling for clinical 48/751 (6.4%) – 61 had an incomplete Baseline characteristics of two
Country: USA Evidence Level: II GA = 35 weeks and BW = 2500 g risk factor model groups not compared
follow-up Confounding variables
14 n = 812 2) Comparison of diagnostic 1) Association of factors with significant controlled

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