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Nutritional Treatments in Psychiatry  |  57

          Digestive disorders, such as Crohn’s Disease, that inhibit
          nutritional absorption, can contribute to a deficiency state in
          these and other nutrients. Low magnesium can cause depressive
          symptoms, confusion, anxiety, and hallucinations; calcium
          deficiency can lead to nervousness, apprehension, and
          numbness. Often supplemented together in approximately a 2:1
          calcium-magnesium ratio, this combination is well-known in the
          CAM world as a calmant and muscle relaxer.
           Magnesium deficiency has been linked to depression and other
          psychiatric disorders (Barbagallo 2009). A study of older diabetic
          patients found that the prevalence of low serum magnesium was
          3.5 times higher amongst depressed individuals compared to
          controls (Barragan-Rodríguez 2007). Follow-up research by the
          same team showed that magnesium treatment of depression in
          elderly diabetics was as effective as imipramine therapy
          (Barragan-Rodríguez 2008).
           Calcium carbonate supplementation, in the form of 1200 mg of
          elemental calcium daily, was given to 497 women between the
          ages of 18 and over a range of three menstrual cycles. The
          researchers concluded: “Calcium supplementation is a simple
          and effective treatment in premenstrual syndrome, resulting in
          a major reduction in overall luteal phase symptoms.” (Thys-
          Jacobs 1998)

          Summary
          Nutritional psychiatry has come a long way since Hoffer and
          Osmond’s first double-blind studies in the 1950s. Through the
          extensive research of neurochemistry and related fields over the
          past decades and ample clinical evidence, the logic behind the
          therapeutic use of vitamins, minerals, and other nutrients has
          become clear. Hopefully, it is also evident that, for many
          patients, psychiatric symptoms are warning signs of nutritional
          deficiency that impact physical status as well. Failure to address
          these nutritional deficits may not only result in little or no
          change in the patient’s complaints but, as when any medical
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