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The Comprehensive Medical Exam in Psychiatry  |  33

                           NODE A
             1. Serum T4 <4.5 mcg/dL or free T4 < 1 ng/dL   YES (to
             2. Hematocrit < 39% (m) or < 35% (f)    any)
             3. Hematocrit > 56% (m) or > 52% (f)
             4. White blood count < 4100/cu mm

             5. Serum aspartate aminotransferase (SGOT) >150   Disease
              IU/L                                     likely
             6. Serum albumin < 2.0 gm/dL             L.R. = 6.4
           7. Serum calcium > 12.0 mg/dL
              8. Glycosuria (by dipstick)

                 Disease less
                   likely         NO (to all)     YES (to
                                                  any)
                         NODE B
             1. History of epilepsy                  Disease
             2. History of emphysema                 likely
             3. History of blood or pus in the urine   L.R. = 5.7
             4. Hematuria (by dipstick) in male aged
              over 50 years

              Disease less likely   NO (to all)
                 L.R. = 0.58
                                                 YES (to
                         NODE C                   any)
             1. History of diabetes
             2. Serum T4 > 12.5 mcg/dL or free T4 > 4.4   Disease
             ng/dL                                    likely
              3.Proteinuria (by dipstick)           L.R. = 2.75
             4. Serum aspartate aminotransferase
              (SGOT) > 60 IU/L or serum alanine
           aminotransferase (SGPT) > 75 IU/L


               Disease less likely   NO (to all)
                  L.R. = 0.58
           Figure 2.1—The Koran Algorithm. L.R. = Likelihood Ratio. (Courtesy of
          Christine Marr.)
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