Page 13 - Chiral N,N-Dioxides: New Ligands and Organocatalysts for Catalytic Asymmetric Reactions

Chiral N,N -Dioxides Liu et al.
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Ph.D. from the Chinese Academy of Sciences under the supervision 18 Hou, Z. R.; Wang, J.; Liu, X. H.; Feng, X. M. Highly Enantioselective Strecker Reaction of
of Professors Zhitang Huang and Yaozhong Jiang. He went to the Ketoimines Catalyzed by an Organocatalyst from (S)-BINOL and L-Prolinamide. Chem.;
Eur. J. 2008, 14, 4484–4486.
Chengdu Institute of Organic Chemistry, Chinese Academy of
19 Cai,Y. F.;Wang,W. T.;Shen, K.; Wang, J.;Hu, X. L.;Lin, L. L.; Liu, X. H.; Feng,X. M. Highly
Sciences (19962000) and was appointed as a professor in Enantioselective R-Chlorination of Cyclic β-Ketoesters Catalyzed by N,N -Dioxide Using
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1997. He did postdoctoral research at Colorado State University NCS as the Chlorine Source. Chem. Commun. 2010, 46, 1250–1252.
20 Zhang, X.; Chen, D. H.; Liu, X. H.; Feng, X. M. Enantioselective Allylation of
(19981999) with Professor Yian Shi. In 2000, he moved to Ketones Catalyzed by N,N -Dioxide and Indium(III) Complex. J. Org. Chem. 2007,
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Sichuan University as a professor, focusing on the design of chiral 72, 5227–5233.
catalysts, development of new synthetic methods, and synthesis of 21 Yu,Z.P.;Liu, X.H.;Dong, Z. H.;Xie,M.S.; Feng,X.M.AnN,N -Dioxide/In(OTf) 3 Catalystfor
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bioactive compounds. the Asymmetric Hetero-DielsAlder Reaction between Danishefsky's Dienes and Alde-
hydes: Application in the Total Synthesis of Triketide. Angew. Chem., Int. Ed. 2008, 47,
1308–1311.
We are sincerely indebted to a highly talented group of co-workers 22 Shang, D. J.; Xin, J. G.; Liu, Y. L.; Zhou, X.; Liu, X. H.; Feng, X. M. Enantioselective
Aza-DielsAlder Reaction of Aldimines with Danishefsky-Type Diene Catalyzed
whosenamesarelistedinthe relevant references. We also thankthe by Chiral Scandium(III) N,N -Dioxide Complexes. J. Org. Chem. 2008, 73,630–
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National Natural Science Foundation of China (Nos. 20732003 637.
23 Guillaneux, D.; Zhao, S.-H.; Samuel, O.; Rainford, D.; Kagan, H. B. Nonlinear Effects in
and 21021001), the Major Basic Research Development Program Asymmetric Catalysis. J. Am. Chem. Soc. 1994, 116, 9430–9439.
(973 program: No. 2010CB833300), and Sichuan University for 24 Xie, M. S.; Chen, X. H.; Zhu, Y.; Gao, B.; Lin, L. L.; Liu, X. H.; Feng, X. M. Asymmetric
Three-Component Inverse ElectronDemand Aza-DielsAlder Reaction: Efficient
financial support. Synthesis of Ring-Fused Tetrahydroquinolines. Angew. Chem., Int. Ed. 2010, 49,
3799–3802.
25 Zhu, Y.; Chen, X. H.;Xie,M.S.; Dong,S.X.; Qiao,Z.; Lin, L. L.;Liu, X.H.; Feng, X. M.
FOOTNOTES Asymmetric DielsAlder and Inverse Electron Demand Hetero-DielsAlder Reactions of
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*To whom correspondence should be addressed. E-mail: xmfeng@scu.edu.cn. β,γ-Unsaturated R-Ketoesters with Cyclopentadiene Catalyzed by N,N -Dioxide Copper(II)
Complex. Chem.;Eur. J. 2010, 16, 1196311968 and references therein.
26 Shen, K.; Liu, X. H.; Zheng, K.; Li, W.; Hu, X. L.; Lin, L. L.; Feng, X. M. Catalytic Asymmetric
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