Page 50 - Cardiac testing for coronary artery disease in potential kidney transplant recipients

Ferreira 2007 (Continued)

Reference standard results blinded? Yes The measurement bias was controlled
All tests through the “blind” interpretation of the
test regarding the coronary angiography,
which was considered the reference stan-
dard

Index test results blinded? Yes The recorded images were later interpreted
All tests by two members who were blinded to the
patients’ clinical data, as independent ob-
servers. The discordance was solved by con-
sensus between the two observers

Relevant clinical information? Yes Relevant clinical information was provided
All tests regarding the performance and analysis of
both the index and reference tests
Uninterpretable results reported? Yes Of 148 patients submitted to the test, 135
All tests finished the protocol, which corresponds to
a feasibility of 91%. The reasons that led
to test interruption were: attaining 85% of
maximum CF for age: 121 (81%); limiting
side effects: 13 (9%); echocardiographic
signs of ischaemia: 10 (7%) and end of the
protocol: 4 (3%)

Withdrawals explained? Yes Thirteen patients presented an early with-
All tests drawal of the protocol due to limiting side
effects: 12 (8.5%) due to hypertensive re-
sponse and 1 (0.5%) due to severe angina

Gang 2007

Clinical features and settings Clinical features
• Patients with DM and ESKD who presented for kidney transplant cardiac
evaluation
Setting
• Muljibhai Patel Urological Hospital, Gujarat, India

Participants • Number: 40
• Type 2 DM: 100%
• ESKD: 100%
• Angina pectoris: 5%
• Hypertension: 92%
• Sex: 90% male

Study design Cross sectional study.

Cardiac testing for coronary artery disease in potential kidney transplant recipients (Review) 48
Copyright © 2011 The Cochrane Collaboration. Published by John Wiley & Sons, Ltd.