Page 44 - Cardiac testing for coronary artery disease in potential kidney transplant recipients

P. 44

Brennan 1997 (Continued)

Representative spectrum? Yes Patients with ESKD at risk of CAD who
All tests presented for kidney transplant cardiac
evaluation

Acceptable reference standard? Yes Coronary angiography with a reference
All tests standard threshold of ≥ 50% stenosis

Acceptable delay between tests? Yes Average time from DSE to coronary an-
All tests giography < 9 months (author correspon-
dence)

Partial veriﬁcation avoided? No Of the 47 patients who underwent DSE,
All tests 5 who tested positive underwent coronary
angiography, and 7 others who had nega-
tive DSE results also underwent coronary
angiography. The reason that patients who
were index test negative underwent coro-
nary angiography was for other than clini-
cal or high pre-test suspicion (author cor-
respondence)

Differential veriﬁcation avoided? Yes Disease status (CAD) diagnosed by coro-
All tests nary angiography.

Incorporation avoided? Yes Disease status (CAD) diagnosed by coro-
All tests nary angiography.

Reference standard results blinded? No It is probable that the person who per-
All tests formed the coronary angiogram was aware
of the DSE result. However, because later
coronary angiograms were performed by an
outside institution, this was not necessarily
the case (author correspondence)

Index test results blinded? Yes All studies were reviewed independently by
All tests two experienced echocardiographers who
were blinded to the clinical data

Relevant clinical information? Yes Relevant clinical information was provided
All tests regarding the performance and analysis of
both the index and reference tests
Uninterpretable results reported? Yes No results were reported to be uninter-
All tests pretable.

Withdrawals explained? Yes All patients missing from the ﬁnal analysis
All tests were accounted for

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